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近日,华西基础医学与法医学院刘肖珩教授团队在Bone Research发表原创研究论文,证实了基质囊泡来源的AnxA5在骨重塑中的重要作用,阐明了AnxA5通过促进基质囊泡与I型胶原的黏附,诱导骨前体细胞发生自噬和加速矿化预防骨丢失的新机制,为骨质疏松症的防治提供新策略。
近日,由西北工业大学生命学院骞爱荣教授和胡丽芳副教授主编的英文专著《BONE CELL BIOMECHANICS, MECHANOBIOLOGY, AND BONE DISEASES》(中文译名:骨细胞生物力学、力学生物学和骨疾病)在国际知名出版社爱思唯尔(ELSEVIER)正式出版。
A Cornell-led collaboration has been awarded a five-year, $3.6 million grant from the National Institutes of Health to explore the ways that the gut microbiome – that mass of microorganisms inside us ...
2018年5月24日,国际学术期刊Bone Research在线发表了中国科学院生物化学与细胞生物学研究所邹卫国研究组的综述文章“Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts”。该文章系统阐述了成骨细胞...
Background: Little is known about bone mineral density (BMD) during pregnancy. Advances in technology with lower radiation emissions by dual-energy X-ray absorptiometry instruments now permit the safe...
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
Background: Age-related estrogen deficiency leads to accelerated bone resorption. There is evidence that, through selective estrogen receptor modulation, isoflavones may exert beneficial effects again...
Background: Age-related estrogen deficiency leads to accelerated bone resorption. There is evidence that, through selective estrogen receptor modulation, isoflavones may exert beneficial effects again...
The systematic review of dietary protein and bone health and falls in the current issue of the Journal by Shams-White et al. (1) is thorough and timely. Their key findings are that dietary protein int...
Background: Considerable attention has recently focused on dietary protein’s role in the mature skeleton, prompted partly by an interest in nonpharmacologic approaches to maintain skeletal health in a...
Background: Bone mineral content (BMC) and bone mineral density (BMD) are positively correlated with dietary protein intakes, which account for 1–8% of BMC and BMD variances. However, the relation bet...
Background: The mechanism and clinical significance of low circulating 25-hydroxyvitamin D [25(OH)D] in obese people are unknown. Low total 25(OH)D may be due to low vitamin D–binding proteins (DBPs) ...
Growth factors play an important role during early ovarian development and folliculogenesis, since they regulate the migration of germ cells to the gonadal ridge. They also act on follicle recruitment...
Bone cells can sense physical forces and convert mechanical stimulation conditions into biochemical signals that lead to expression of mechanically sensitive genes and proteins. However, it is still p...

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