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【应化系学术报告2023-03】From DNA damage to DNA sensing: bridging innate and adaptive immunity（图）
DNA damage DNA sensing innate adaptive immunity
2023/6/20
【应化系学术报告2023-03】From DNA damage to DNA sensing: bridging innate and adaptive immunity
Protection of Bovine Mammary Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Cell Damage by Selenium
selenomethionine selenoprotein synthesis arachidonic acid metabolism mitogen-activated protein kinase
2018/3/5
The uncontrolled release of arachidonic acid (ARA) and its metabolism by lipoxygenase (LOX) pathway can induce
and aggravate cellular oxidative stress. Selenium (Se) is an integral part of some antio...
Deer prefer native plants leaving lasting damage on forests
Deer native plants lasting damage forests
2017/10/25
When rampant white-tailed deer graze in forests, they prefer to eat native plants over certain unpalatable invasive plants, such as garlic mustard and Japanese stiltgrass. These eating habits lower na...
第八届DNA损伤应答与人类疾病国际研讨会（isDDRHD-2017）（8th international symposium on DNA Damage Response&Human Disease）
第八届 DNA损伤应答与人类疾病 国际研讨会
2017/8/31
第八届DNA损伤应答与人类疾病国际研讨会（international symposium on DNA Damage Response & Human Disease, isDDRHD-2017）将于2017年10月27-29日在深圳大学召开。DNA损伤应答与人类疾病国际研讨会（isDDRHD）是由许兴智教授和Zhao-Qi Wang院士于2010年共同发起，旨在为DNA修复领域的中国学者与国际主...
Prion study reveals how abnormal proteins damage nerve cells in the brain
Prion study abnormal proteins damage nerve cells the brain
2017/7/20
A new study has uncovered a molecular mechanism in the prion protein that may explain why nerve cells degenerate in prion diseases such as Creutzfeldt-Jakob disease (CJD).The findings, which appear in...
Spatially localized generation of nucleotide sequence-specific DNA damage
sperm chemotaxis fertilization TPX-1 AEG CRISP
2016/5/23
Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate tha...
Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study
Recovery, BCAA Muscle damage Resistance training
2015/7/23
It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and
causes soreness and discomfort. Branched-chain amino acid (BCAA) supplementation has been shown to incre...
The Role Of ERα, ERβ And Phytoestrogens From Soy In P53- Mediated Response To Dna Damage In Mammary Epithelium
Biological sciences Breast cancer Estrogen receptors Mammary tumors p53 Phytoestrogens DNA damage
2014/12/11
Estrogenic compounds can stimulate proliferation of the mammary epithelium, but also potentiate the activity of the p53 tumor suppressor protein. These contradictory activities of estrogenic compounds...
Engineering a protein to prevent brain damage from toxic agents
Engineering a protein prevent brain damage toxic agents
2014/8/14
Research at New York University is paving the way for a breakthrough that may prevent brain damage in civilians and military troops exposed to poisonous chemicals—particularly those in pesticides and ...
Protective Efficacy of Alpha-lipoic Acid against AflatoxinB1-induced Oxidative Damage in the Liver
AflatoxinB Alpha-lipoic Acid Liver Oxidative Damage Antioxidant
2016/5/16
Alpha-lipoic acid (α-LA) is not only involved in energy metabolism, but is also a powerful antioxidant that can protect against hepatic oxidative stress induced by some drugs, toxins, or under various...
Effects of α-lipoic Acid on mtDNA Damage after Isolated Muscle Contractions
ISOLATED EXERCISE >-LIPOIC ACID PROPHYLAXIS MITOCHONDRIAL DNA DAMAGE LIPID PEROXIDATION
2017/7/17
ntroduction: Although pharmacological antioxidants have previously been investigated for a prophylactic effect against exercise oxidative stress, it is not known if α-lipoic acid supplementation can p...
Global study shows brain damage from stroke can be minimised
brain damage electroencephalogram
2014/7/15
A new study from The University of Queensland shows monitoring the brain of stroke patients using Quantitative EEG (QEEG) studies could inform treatments and therefore, minimising brain damage of stro...
A Mathematical Model for Estimating Biological Damage Caused by Radiation
cell density radiation protection radiation risk apoptosis mutation DNA repair mathematical model low-dose exposure irradiation rate Living object
2012/4/20
We propose a mathematical model for estimating biological damage caused by low-dose irradiation. We understand that the Linear Non Threshold (LNT) hypothesis is realized only in the case of no recover...
Multiscale QM/MM Molecular Dynamics Study on the First Steps of Guanine-Damage by Free Hydroxyl Radicals in Solution
Multiscale QM/MM Molecular Dynamics the First Steps Guanine-Damage Free Hydroxyl Radicals Solution
2012/2/28
Understanding the damage of DNA bases from hydrogen abstraction by free OH radicals is of particular importance to reveal the effect of hydroxyl radicals produced by the secondary effect of radiation....
Abstract: This paper is devoted to the analysis of the complex damage of DNA irradiated by ions. The analysis and assessment of complex damage is important because cells in which it occurs are less li...