搜索结果: 1-8 共查到“膜生物化学 DNA”相关记录8条 . 查询时间(0.375 秒)
近期，智能所智能微纳器件研究室张忠平研究员和王振洋研究员领导的团队在生物体核酸结构的同步原位影像分析方面取得重要进展，合成了一种具有高效生物膜穿透能力的阳离子碳量子点，实现了对活细胞及线虫体内DNA和RNA的同步荧光成像。相关研究成果发表在国际著名化学期刊《德国应用化学》 （Angew. Chem. Int. Ed.）上。这是继该团队两个月前在该杂志发表细胞及生物体多通道荧光影像分析研究成果后的又...
DNA-Based Patterning of Tethered Membrane Patches
DNA Lipids Lipid Bilayers Molecular Structure Particle Size Surface Properties
2016/5/25
Solid-supported lipid bilayers are useful model systems for mimicking cellular membranes; however, the interaction of the bilayer with the surface can disrupt the function of integral membrane protein...
Individual Vesicle Fusion Events Mediated by Lipid-anchored DNA
Cholesterol DNA Lipid Bilayers Phosphatidylcholines Phosphatidylethanolamines Membrane Fusion Unilamellar Liposomes
2016/5/25
Membrane fusion consists of a complex rearrangement of lipids and proteins that results in the merger of two lipid bilayers. We have developed a model system that employs synthetic DNA-lipid conjugate...
Formation and Analysis of Topographical Domains Between Lipid Membranes Tethered by DNA Hybrids of Different Lengths
Cell Membrane DNA Membrane Lipids Lipid Bilayers 1,2-Dipalmitoylphosphatidylcholine Microscopy, Fluorescence Base Sequence Molecular Sequence Data Models,Chemical Unilamellar Liposomes
2016/5/25
We recently described a strategy to prepare DNA-tethered lipid membranes either to fixed DNA on a surface or to DNA displayed on a supported bilayer [Boxer et al., J. Struct. Biol., 2009, 168, 190; Bo...
Stability of DNA-Tethered Lipid Membranes with Mobile Tethers
Metallic glasses Rapid-solidification Microstructure Mechanical properties
2016/5/25
We recently introduced two approaches for tethering planar lipid bilayers as membrane patches to either a supported lipid bilayer or DNA-functionalized surface using DNA hybridization (Chung, M.; Lowe...
Covalent Attachment of Lipid Vesicles to a Fluid-Supported Bilayer Allows Observation of DNA-Mediated Vesicle Interactions
Caspian and Black Sea waters reverse-osmotic desalination Na-zeolite softening of the permeate
2016/5/25
Specific membrane interactions such as lipid vesicle docking and fusion can be mediated by synthetic DNA-lipid conjugates as a model for the protein-driven processes that are ubiquitous in biological ...
DNA-tethered Membranes Formed by Giant Vesicle Rupture
Tethered lipid membrane Surface immobilized DNA Giant unilamellar vesicles
2016/5/25
We have developed a strategy for preparing tethered lipid bilayer membrane patches on solid surfaces by DNA hybridization. In this way, the tethered membrane patch is held at a controllable distance f...
Kinetics of DNA-mediated Docking Reactions Between Vesicles Tethered To Supported Lipid Bilayers
DNA electron transfer oxidative stress redox regulation
2016/5/25
Membrane-membrane recognition and binding are crucial in many biological processes. We report an approach to studying the dynamics of such reactions by using DNA-tethered vesicles as a general scaffol...