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近日,合成生物学领域国际知名期刊《代谢工程》(Metabolic Engineering)在线发表了武汉大学药学院、中南医院药学研究院、泰康生命医学研究中心邓子新院士团队陈文青教授课题组关于“搭建大肠杆菌平台,智造核苷类医药中间体”的重要研究成果。武汉大学为该论文的第一署名单位,博士研究生于乐、高耀杰为共同第一作者,陈文青教授为通讯作者。
“Harder, better, faster, stronger”:tethered soft exosuit reduces the metabolic cost of running
Harder better faster stronger tethered soft exosuit reduces metabolic cost of running
2017/7/21
What if running the 26.2 miles of a marathon only felt like running 24.9 miles, or if you could improve your average running pace from 9:14 minutes/mile to 8:49 minutes/mile without weeks of training?...
2016冷泉港学术会议:代谢信号机制(Cold Spring Harbor conference on Mechanisms of Metabolic Signaling)
Genetics Genomes
2017/1/19
Metabolic regulation is at the intersection of many scientific fields, ranging from basic biochemistry and molecular biology to physiology, to the study of disease pathogenesis. Currently, a major cha...
Resting metabolic rate in obese and nonobese Chinese Singaporean boys aged 13–15 y
fat mass fat-free mass analysis of covariance
2016/6/14
Previous studies investigating the hypothesis that
a low resting metabolic rate (RMR) is a cause of obesity yielded
discrepant findings. Two explanations for these findings are the
use of imprecise...
Similar metabolic responses to standardized total parenteral nutrition of septic and nonseptic critically ill patients
sepsis critically ill patients severity of illness
2016/6/14
Nutritional support is an important link between
the response to injury and recovery in critical illness.
Functional and metabolic early changes in calf muscle occurring during nutritional repletion in malnourished elderly patients
inorganic phosphate glycogen isokinetic peak torque
2016/6/13
Metabolic alterations in skeletal muscle associated
with malnutrition and the potential reversibility of such
alterations during refeeding are not fully understood.
Postprandial de novo lipogenesis and metabolic changes induced by a high-carbohydrate, low-fat meal in lean and overweight men
Obesity hyperinsulinemia carbohydrates
2016/6/12
Adjustments of carbohydrate intake and oxidation
occur in both normal-weight and overweight individuals. Nevertheless,
the contribution of carbohydrates to the accumulation of
fat through either re...
Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women
cardiovascular disease glycemia lipidemia
2016/6/12
The influence of the amount and type of carbohydrates
in the diet on risk factors for obesity, diabetes, and cardiovascular
disease remains unclear.
Metabolic precursors and effects of obesity in children: a decade of progress, 1990–1999
white children obesity body composition
2016/6/12
Current data suggest that 20% of US children
are overweight. An analysis of secular trends suggested a clear
upward trend in body weight in children of 0.2 kg/y between
1973 and 1994. In addition, ...
Metabolic and behavioral consequences of a snack consumed in a satiety state
Snack appetite control satiety
2016/6/1
In view of the influence of dietary habits on obesity,
human eating patterns merit study.
National Institutes of Health workshop: Role of Nutrient Regulation of Signal Transduction in Metabolic Diseases
Signal Transduction Metabolic Diseases
2016/6/1
Nutritive and nonnutritive dietary constituents can promote or
hinder the development of several chronic diseases, including
cancer, obesity, inflammatory diseases, diabetes, and cardiovascular
dis...
Meta-analysis of resting metabolic rate in formerly obese subjects
Body composition fat-free mass fat mass
2016/5/31
A low resting metabolic rate (RMR) for a given
body size and composition is partly genetically determined and
has been suggested to be a risk factor for weight gain. Moreover,
a low relative RMR ha...
Influence of the metabolic sequelae of liver cirrhosis on nutritional intake
Liver cirrhosis primary biliary cirrhosis hepatocellular cirrhosis
2016/5/30
The liver plays a central role in ingestive behavior;
alterations in metabolic signaling to the brain stem as a
result of chronic liver disease could influence intake.
Metabolic and weight-loss effects of a long-term dietary intervention in obese patients
Weight loss biomarkers disease risk
2016/5/30
Obesity is a chronic disease that has become one
of the most serious health problems in Western society