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The effects of nicotinic acid on testicular atrophy caused by di（2-ethylhexyl）phthalate（DEHP）and metal concentrations in the atrophic testes
di-(2-ethylhexyl) phthalate (DEHP) testicular atrophy testicular metal concentrations
2009/4/1
Di-(2-ethylhexyl) phthalate (DEHP) is the most common plasticizer for plastics such as polyvinyl chloride. However, recent studies have demonstrated toxic effects of DEHP on the testes and liver in ro...
2,5-hexanedione exposure in the rat results in long-term testicular atrophy despite the presence of residual spermatogonia
Germ cell repopulation Sertoli cell toxicity spermatogonia
2009/2/7
Charles River CD rats (approximate weight, 208 g) were exposed to 1.0% 2,5-hexanedione (2,5-HD) in drinking water for 5 weeks. Rats were killed 27, 60, and 75 weeks after exposure to evaluate the re...