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Alteration of endogenous corticosteroids and catecholamines in allergen-induced eosinophilic inflammation in Brown Norway rats
airway inflammation asthma Brown Norway rat endogenous corticosteroid metabolic cage urinary catecholamine excretion urinary 11-hydroxycorticosteroid excretion
2010/11/29
Although various types of stress activate a pituitary adrenal response, the alteration of endogenous corticosteroids and catecholamines during asthma remains unclear. The aim of this study was to asse...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...
Differential effects of corticosteroids and theophylline on the adhesive interaction between eosinophils and endothelial cells
cell adhesion corticosteroids endothelial cells eosinophils theophyline
2010/11/22
Corticosteroids and theophylline have been used widely for the treatment of asthma. These two classes of drugs appear to reduce the tissue infiltration of eosinophils, predominant inflammatory cells i...
Effect of Transdermal Tulobuterol Added to Inhaled Corticosteroids in Asthma Patients
bronchial asthma long-acting β2-agonist transdermal therapeutic system tulobuterol tape
2010/11/22
In patients with persistent asthma who require inhaled short-acting β2-agonists while receiving inhaled corticosteroids, transdermal tulobuterol significantly improved PEF in a dose-dependent manner, ...
Improvement of Reduced Bone Mineral Density by Intermittent Cyclical Etidronate in Postmenopausal Asthmatic Patients Receiving Inhaled Corticosteroids
bisphosphonate bronchial asthma inhaled corticosteroids osteoporosis postmenopausal women
2010/11/19
Background: We have recently shown that early postmenopausal but not premenopausal asthmatic women treated with inhaled corticosteroids demonstrate reduced bone mineral density (BMD) and decreased ser...