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The Effect of Natural Adjuvants on Pathological Changes in Sensitized Guinea Pig Lungs
Asthma Lung Pathology
2015/10/10
Background:: Anti-inflammatory effect of natural adjuvants has been reported. Lung inflammation is the most characterized pathological feature in asthma.
Effects of vitamin A and C and melatonin on 3-nitrotyrosine formation in guinea pig heart under lipopolysaccharide-induced stress
Lipopolysaccharide peroxynitrite 3-nitrotyrosine vitamin A vitamin C melatonin
2010/10/14
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O2.-). O2.- can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrot...
Effect Of Pentoxifylline On The Healing Of Guinea Pig Perforated Tympanic Membrane
Guinea pig pentoxifylline tympanic membrane perforation
2009/12/24
Background: Tympanic membrane perforation as a sign of different otologic disorders have multiple causes, for example trauma .Traumatic perforations heal spontaneously in most cases but in large and s...
A Comparative Analysis of Perinatal Development of Barrel Cortex in Rat,Mouse and Guinea Pig Using Acetylcholinesterase Histochemistry
Thalamocortical development barrel cortex rodent and acetylcholinesterase histochemistry
2009/6/30
The role of acetylcholinesterase (AChE) in the developing neocortex was reexamined by comparing its expression in rats, mice and guinea pigs, following the protocol for acetylcholinesterase histochemi...
Effects of KP-496, a Novel Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors, on Contractions Induced by Various Agonists in the Guinea Pig Trachea
antagonist anti-asthmatic drugs asthma leukotriene D4 thromboxane A2
2010/11/19
KP-496 produced parallel rightward shifts of the LTD4 and U46619 concentration-response curves in a concentration-dependent manner. Schild plot analyses of the antagonistic activities of KP-496 demons...
In vitro Comparison of the Intrinsic Activity of Functional Antagonism between β-agonists and Spasmogens in the Guinea-pig Tracheal Muscle
carbachol contraction functional antagonism guinea-pig trachea intrinsic activity potency β-agonists
2010/11/19
Relaxation responses to β-agonists were diminished depending on the extent of carbachol-induced tone in the tracheal muscle. The degree of hyporesponsiveness was greatest in treatment with tulobuterol...