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PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYMES REGULATE DEATH ASSOCIATED PROTEIN KINASE (DAPK) IN CERAMIDE-INDUCED ANOIKIS
PROTEIN PHOSPHATASE 2A DAPK DEATH ASSOCIATED PROTEIN KINASE
2015/5/22
Modulation of sphingolipid-induced apoptosis is a potential mechanism to enhance the effectiveness of chemotherapeutic drugs. Ceramide is a pleiotropic, sphingolipid produced by cells in response to i...
Death-Associated Protein Kinase Regulates Vascular Smooth Muscle Cell Signaling and Migration
p65 MMP9 atherosclerosis
2015/5/22
Cardiovascular disease is the number one cause of death for Americans. New treatments are needed for serious conditions like atherosclerosis, as it can lead to stroke and heart attack. Many types of c...
Role of protein kinase A in the inhibition of human mast cell histamine release by β-adrenergic receptor agonists
β-adrenergic receptor agonist histamine release human cultured mast cells protein kinase A protein kinase C
2010/11/24
Stimulation of mast cells induced the elevation of intracellular cytosolic free Ca2+ concentrations ([Ca2+]i) and the translocation of protein kinase C (PKC) from the cytosol to the cell membrane, fol...
Role of protein kinase C and calmodulin in histamine release in experimental filariasis
Brugia malayi calmodulin histamine lung mast cells Mastomys natalensis peritoneal mast cells protein kinase C
2010/11/29
The allergenic activity of 60 kDa antigen of Brugia malayi adult worm, due to its ability to release histamine from mast cells, has been previously reported by us. To determine the roles of protein ki...