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The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion
Indazole-carboxylic acids tolnidamine antispermatogenic agents Sertoli cell
2009/2/23
The indazole-carboxylic acid derivative tolnidamine (TOL) has marked antispermatogenic activity in rats. Previous morphological and biochemical studies indicate that Sertoli cells are one of the tar...
Identification of a potential FSH modulatory protein in human testis and seminal plasma
potential FSH modulatory protein human testis seminal plasma
2009/2/23
A variety of factors capable of inhibiting the in vitro binding of FSH to its receptor have been identified in gonadal tissues from males and females. Interest in these factors has been stimulated b...
Identification of androgen binding-protein（ABP）from testis and epididymis of the seasonal rodent, Octodon degus（Molina, 1872）
androgen binding-protein (ABP) testis seasonal rodent Octodon degus (Molina, 1872)
2009/2/23
ABP, a Sertoli cell secretory product, was identified in the seasonal rodent Octodon degus (Molina, 1872). It was shown to be present in cytosols from the testis and epididymis. It migrated with a...
Incorporation of gossypol and formation of its protein conjugates in mouse transformed Sertoli（TM4）cells
protein conjugates mouse transformed Sertoli（TM4）cells
2009/2/23
Mitochondria of both mouse transformed Sertoli (TM4) cells and primary-cultured rat and mouse Sertoli cells were shown to be preferentially affected by gossypol (Tanphaichitr et al, 1984). To invest...
Localization of the human prostatic secretory protein PSP94 and its mRNA in the epithelial cells of the prostate
man prostate protein mRNA epithelium secretion
2009/2/23
The histologic distribution of a prostatic secretory protein of 94 amino acids (PSP94) and its mRNA were examined simultaneously by conventional immunohistochemistry and in situ hybridization histoc...
Effect of germ cells on vectorial secretion of androgen binding protein and transferrin by immature rat Sertoli cells in vitro
germ cells vectorial secretion androgen binding protein transferrin immature rat Sertoli cells
2009/2/23
The influence of germ cells (greater than 85% pachytene spermatocytes) on vectorial secretion of androgen binding protein (ABP) and transferrin by immature rat Sertoli cells was investigated using t...
The heterogeneity of rat androgen binding protein（rABP）in the vascular compartment differs from that in the testicular tubular lumen. Further evidence for bidirectional secretion of rABP
rat ABP ABP heterogeneity
2009/2/23
Fractionation of testicular extracts and serum on a Concanavalin A-Sepharose column resolved two peaks of immunoreactive rat androgen binding protein. The rat androgen binding protein in the first pea...
Concentrations of free testosterone, total testosterone, and androgen binding protein in the peripheral serum of male rats during sexual maturation
free testosterone total testosterone androgen binding protein peripheral serum male rats
2009/2/23
To investigate the relationship between free testosterone and sexual maturation in the male rat, animals were decapitated every 5 days from 25 through 75 days of life. Serum was assayed for androgen...
A comparative analysis of cAMP-dependent protein kinase regulatory subunits in sea urchin and rat spermatozoa
spermatozoa azido photoprobes protein kinase nucleotides epididymis
2009/2/23
8-Azido cAMP photoaffinity labeling of cAMP-dependent protein kinase regulatory subunits (R1 = 49 K;R2 = 55K) was done on spermatozoa from species lacking, and species containing an epididymis. Sper...
Localization of cellular retinol-binding protein and cellular retinoic acid-binding protein in the rat testis and epididymis
cellular retinol-binding protein cellular retinoic acid-binding protein rat testis
2009/2/20
The distribution of cellular retinol-binding protein (CRBP) and cellular retinoic acid-binding protein (CRABP) in rat testis and epididymis was examined by the peroxidase-antiperoxidase immunolocali...
The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function：I. Early changes in androgen binding protein secretion in the rat
tolnidamine rABP LH FSH testosterone
2009/2/20
The indazole carboxylic acid derivative, tolnidamine, has marked antispermatogenic activity in several animal species. In this study, we assessed the effect of tolnidamine on rat Sertoli cell functi...
Secretion of androgen binding protein by Sertoli cells is influenced by contact with germ cells
androgen binding protein Sertoli cells germ cells
2009/2/20
Sertoli cells were cultured alone or with germ cells to evaluate the effect of the association with germ cells on the secretory activity of Sertoli cells. Secretion of androgen-binding protein, whic...
Protein secretion by the rat epididymis can be selectively modified in vitro by local anesthetics, glucose deprivation, dinitrophenol, ouabain, and ionophores
Protein secretion rat epididymis selectively modified local anesthetics
2009/2/20
Protein secretion by the caput epididymidis has been examined in vitro using radioactive methionine as a precursor for protein synthesis. Newly synthesized and secreted proteins were separated by gel ...
Identification of arginine esterase as the major androgen-dependent protein secreted by dog prostate and preliminary molecular characterization in seminal plasma
arginine esterase dog prostate seminal
2009/2/20
This work was undertaken to determine the identity of the major androgen-dependent 15,000 molecular weight protein previously observed on SDS polyacrylamide gel electrophoresis of both dog prostate ...
Growth and reproductive adaptation in male rats with chronic protein deficiency
protein deficiency undernutrition testicular
2009/2/20
In previous studies, male rats fed a low-protein diet beginning at weaning were found to have impaired sexual development through age 11 weeks when compared to food-restricted, weight-matched contro...