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Effects of diazacholesterol dihydrochloride（SC-12937）, an avian antifertility agent, on rat testis
testis germ cell Sertoli cell antifertility agent SC-12937 rat
2009/2/23
The present study was undertaken to evaluate the effectiveness of an avian chemosterilant, 20, 25-diazacholesterol dihydrochloride (SC-12937), on the rat testis. Adult male rats were injected intrap...
The male antifertility agents alpha chlorohydrin, 5-thio-D-glucose, and 6-chloro-6-deoxy-D-glucose interfere with sugar transport across the epithelium of the rat caput epididymidis
rat epididymis sugar transport antifertility
2009/2/19
The effects of the male antifertility agents alpha-chlorohydrin, 5-thio-D-glucose, and 6-chloro-6-deoxy-D-glucose on sugar transport (3H-3-O-methyl-D-glucose and 3H-2-deoxy-D-glucose) across the r...
Antifertility Effects of LHRH Agonists in the Male
LHRH agonists LH receptor prolactin receptor LHRH receptor desensitization spermatogenesis
2009/2/18
Acute or chronic treatment of adult male rats with LHRH or its agonists leads to a loss of testicular LH and prolactin receptors accompanied by decreased testis, seminal vesicle, and ventral prost...
Role of Hyaluronidase in Fertilization: The Antifertility Activity of Myocrisin, a Nontoxic Hyaluronidase Inhibitor
myocrisin hyaluronidase inhibitor fertilization contraception
2009/2/18
Myocrisin, a hyaluronidase inhibitor of low molecular weight, was tested for antifertility activity. In addition, the effect of myocrisin on penetration of the follicle cell layer by spermatozoa w...
Antifertility potential of ornidazole analogues in rats
Epididymis contraception nitroimidazoles fertility sperm
2009/2/17
In order to determine which part of the ornidazole molecule [1-(3-chloro-2-hydroxy)propyl-2-methyl-5-nitroimidazole] is responsible for its antifertility action, structural analogues were fed to mal...
Susceptibility of glycolytic enzyme activity and motility of spermatozoa from rat, mouse, and human to inhibition by proven and putative chlorinated antifertility compounds in vitro
glycolytic enzyme activity motility spermatozoa rat mouse human inhibition
2008/12/26
Nonhormonal contraceptives that act by blocking energy metabolism within sperm have the advantage over spermatogenic inhibitors by their fast onset of infertility and their almost immediate restorat...
Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure
Posttesticular antifertility action triptolide male rat sperm ultrastructure
2008/12/25
A variety of active diterpene epoxides, including the triptolide (isolated from Tripterygium wilfordii) have been reported to cause infertility in male rats. Previously, we showed that oral admini...