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Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine
cardiovascular disease plasma S-adenosylmethionine
2016/6/14
Although plasma total homocysteine has been identified
as an independent risk factor for vascular disease in a multitude
of studies, there is a considerable overlap in values between
patients at ri...
Improvements in circulating cholesterol, antioxidants, and homocysteine after dietary intervention in an Australian Aboriginal community
dietary intervention fruit vegetables, cholesterol
2016/6/14
Poor nutrition contributes to high rates of coronary heart
disease among Australian Aboriginal populations. Since late 1993, the
Aboriginal community described here has operated a healthy lifestyle
...
Abstention from filtered coffee reduces the concentrations of plasma homocysteine and serum cholesterol—a randomized controlled trial
Filtered coffee homocysteine cholesterol
2016/6/14
Elevated concentrations of plasma total homocysteine
(tHcy) and serum total cholesterol are risk factors for
ischemic heart disease (IHD). Previous studies showed that the
consumption of very high ...
Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine Study
Total homocysteine cardiovascular mortality cardiovascular disease risk
2016/6/14
Few population-based studies have assessed relations
between plasma or serum total homocysteine (tHcy) and
all-cause mortality.
Plasma concentrations of total homocysteine predict mortality risk
Plasma concentrations total homocysteine
2016/6/14
In this issue of the Journal, investigators from Norway, who
are well known throughout the world for their contributions to the
field of blood homocysteine, have added another important finding
(1)...
Association between B vitamin intake and plasma homocysteine concentration in the general Dutch population aged 20–65 y
Folate riboflavin vitamin B-6 vitamin B-12
2016/6/13
An elevated plasma total homocysteine (tHcy)
concentration is associated with an increased risk of cardiovascular
diseases. Folate, riboflavin, vitamin B-6, and vitamin B-12
are essential in homocy...
Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete
Fasting homocysteine vitamin B-6 riboflavin
2016/6/13
Current data suggest that physiologic doses of
vitamin B-6 have no significant homocysteine-lowering effect.
It is possible that an effect of vitamin B-6 was missed in previous
trials because of a ...
Association of folate intake and serum homocysteine in elderly persons according to vitamin supplementation and alcohol use
Homocysteine tHcy folate
2016/6/13
The serum total homocysteine concentration
(tHcy), an indicator of folate status and a possible risk factor for
vascular disease, is elevated with impaired renal function and
poor vitamin B-12 stat...
Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort
Homocysteine diet folate vitamin B-12
2016/6/13
Established determinants of fasting total homocysteine
(tHcy) concentration include folate and vitamin B-12
status, serum creatinine concentration, and renal function.
Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans
Polyphenol coffee tea
2016/6/12
In population studies, high intakes of coffee are
associated with raised concentrations of plasma homocysteine, a
predictor of risk of cardiovascular disease. Chlorogenic acid is a
major polyphenol...
The article by Koehler et al (1) in this issue of the Journal
points out the complexity of causes of elevated total homocysteine
concentrations (tHcy) in serum and, in particular, raises
interestin...
Total serum or plasma homocysteine (tHcy) is a risk factor for
a series of pathologic conditions, including cardiovascular disease
(1), adverse outcomes and complications of pregnancy (2),
Alzheime...
Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning
Frailty elderly intervention
2016/6/12
Frail elders are at risk of suboptimal micronutrient
status, functional decline, and neurologic disorders. The influence
of oral multimicronutrients in physiologic doses and of
moderately intense p...
Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore
Homocysteine folate vitamin B-12
2016/6/12
Epidemiologic studies have identified the plasma
homocysteine concentration as a risk factor for atherothrombotic
vascular disease. There is little information on the distributions and
determinants...
Recently, Selhub et al (1) pointed out the importance of the
B vitamins folic acid, vitamin B-6, and vitamin B-12 for the
well-being and normal functioning of the brain. They also
mentioned that th...