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Direct measurement of helium elimination in mice
decompression animal mice helium elimination Immersion
2009/7/20
Direct measurement of helium elimination in mice.
Evidence of bacteremia and endotoxemia in mice undergoing hyperbaric stress
animal mice bacteremia endotoxemia Endotoxins microbiology
2009/7/20
Swiss albino mice were exposed to normoxic (PO2 approximately 0.2 ATA) helium at 1, 20 or 35 ATA for 2 or 48 h and examined for the presence of bacteria and endotoxin in selected tissues. Among mice e...
Adrenal function and the incidence of bends after decompression in mice: effect of adrenalectomy,corticosteroids, decompression intensity,and time of day
decompression adrenalectomy decompression intensity
2009/7/17
The adrenocortical endocrine subsystem has been demonstrated to enhance mammalian tolerance to harsh environmental conditions, including hypoxia and temperature extremes. In a series of factorial expe...
Amelioration of decompression sickness in mice by pretreatment with cyproheptadine
decompression animal mice drug
2009/7/17
Substances that stimulate smooth muscle have been previously implicated in the pathogenesis of decompression sickness. This concept was strongly supported by the demonstration that compounds that comb...
Pharmacological evidence for multiple sites of action of pressure in mice
high pressure nervous syndrome animal mice drug heliox
2009/7/16
The ability of eight diverse pharmacological agents to ameliorate the high pressure nervous syndrome (HPNS) in mice was studied. Data were obtained for the end points: coarse tremors, complete spasms,...
Effects of variations in time pattern of nitrogen addition on development of HPNS in mice
drug high pressure nervous syndrome animal mice heliox trimix
2009/7/16
The effect of change in injection pattern in nitrogen on threshold pressures of three symptoms associated with compression in helium/nitrogen atmospheres was explored. Excitement threshold pressures d...
Combination therapy with cell-binding domain,angiogenesis inhibitor and Ca2+ channel blocker in mice metastatic model
Metastasis Cell-binding domain Fibronectin Angiogenesis inhibitor Ca2+ channel blocker
2009/7/15
Background: In order to prevent tumor metastasis, we investigated more effective inhibition by combination therapy. The competition with native adhesion molecules by cell-binding domain, inhibition of...
Sperm maturation associated with subfertility following hyperbaric exposure of mice
animal mice Sperm maturation
2009/7/14
Mice exposed to 50 ATA heliox pressure during one spermatogenic cycle subsequently exhibit subfertility which can recover over an 8-wk period. This study was designed to investigate the changes in spe...
Acute stress augments innate immunity in the liver and increases hyaluronan levels in the tissues and blood of mice
increases hyaluronan levels blood of mice
2009/12/16
The effect of acute stress on the immune system was examined in mice. Restraint stress decreased the number of lymphocytes in the liver, whereas the number of lymphocytes remained unchanged in the spl...
Amino Acid Neurotransmitter Levels in the Cerebral Cortex of Mice Receiving Imipenem/Cilastatin -Lack of Excitotoxicity in the Central Nervous System
Amino acid imipenem mice neurotoxicity
2009/7/2
Imipenem, a very potent carbapenem derivative beta-lactam antibiotic, has recently found a major place in the treatment of antibiotic-resistant nosocomial infections. However, a convulsive side effect...
Nimodipine Aggravates Systemic Kainic Acid Toxicity in Retinal Ganglion Cells of Intact Mice
Kainate retina nimodipine neurotoxicity mice
2009/6/30
The aim of the present study was to investigate the role of the L-type voltage dependent Ca2+ channel blocker, nimodipine, in kainate induced toxicity in retinal ganglion cells of mice. Kainate in 10m...
Immunization of Mice with Plasmid DNA Encoding Hepatitis B Virus Core Antigen (HBcAg)
Hepatitis B virus core antigen DNA immunization
2009/6/25
The aim of this study was to investigate the antibody response following immunization with plasmid vector DNA containing the hepatitis B virus core antigen (HBcAg) gene of a hepatitis B virus (HBV) is...
Effect of Zinc Deficiency on Zinc and Carbohydrate Metabolism in Genetically Diabetic (C57BL/Ksj Db+/Db+) and Non-Diabetic Original Strain (C57BL/Ksj) Mice
Strain zinc depletion diabetic mice (C57BL/KsJdb+/db+) nondiabetic mice (C57BL/KsJ)
2009/6/23
Our aim was to investigate the effect of low dietary zinc intake on zinc and carbohydrate metabolism in type II diabetes. Male, 4–5-week-old, genetically diabetic (C57B/LKsJdb+/db+) and nondiabe...
Effect of Different Drugs Influencing Monoamine Neurotransmission on Haloperidol-Induced Catalepsy in Mice
Catalepsy haloperidol antidepressants mice
2009/6/17
Aim: Catalepsy occurs following high dopamine D2 receptor blockade by the typical antipsychotic drug haloperidol. The present study investigated the effect of different drugs affecting monoamine neuro...
Skin allograft rejection and hyperbaric oxygen treatment in immune-histoincompatible mice
HBO hyperbaric immunosuppressive animal mice animal mice immune
2009/6/12
The effect of hyperbaric oxygen (HBO) as an immunosuppressive agent was evaluated by using a highly immunogenic skin allograft mouse model. Immune-histoincompatible female C57BL/6 and BALB/c mice (N =...