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Academy of Mathematics and Systems Science, CAS Colloquia & Seminars：Fixed Effects Bayesian Testing in High-Dimensional Linear Mixed Models
高维 线性混合模型 固定效应 贝叶斯检验
2023/5/5
Hypothesis testing on high-dimensional fixed effects is indispensable for investigating the utility of the predictors on response. In this case, the conventional frequentist methods designed for cases...
Academy of Mathematics and Systems Science, CAS Colloquia & Seminars：Group-Orthogonal Subsampling for Big Data Linear Mixed Models
大数据 线性混合模型 群正交 子采样
2023/5/10
Linear mixed model is a popular and common modeling method in statistical analysis. It is computationally difficult to obtain parameter estimates in linear mixed model for big data. The current subsam...
Polygenic Modeling with Bayesian Sparse Linear Mixed Models
Polygenic Modeling Bayesian Sparse Linear Mixed Models
2012/11/23
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches ...