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南京农业大学农学院《Plant Physiology》发表郭旺珍教授团队“LIPID TRANSFER PROTEIN4 regulates cotton ceramide content and activates fiber cell elongation”（图）
郭旺珍 脂肪酸 棉纤维发育
2023/10/28
脂肪酸和脂质对植物细胞伸长具有重要作用，其功能特征涉及维持细胞结构完整性，为多种代谢过程提供能量，作为信号转导介质参与多种信号通路等。脂质转运蛋白(LTP)是一种含有疏水腔的蛋白质，这种结构特征使 LTP 蛋白能够结合和转运复杂的脂类物质。棉纤维是世界上最重要的天然纺织原料，也是植物中最长的单细胞。脂类物质的含量及组成对棉纤维发育具有重要调节作用，其中神经酰胺类脂质在棉纤维伸长时期含量最为丰富,且...
Gender and Age Effects on the Expression of Genes Related to Lipid Metabolism in Broiler’s Liver
apolipoprotein lipogenesis lipolysis
2018/3/5
Two experiments were conducted to assess gender (Experiment 1) and age (Experiment 2) effects on the
expression of genes related to lipid metabolism in broiler chickens. The expression of fatty acid ...
Feeding fat to fungi:evidence for lipid transfer in arbuscular mycorrhiza
fat fungi evidence lipid transfer arbuscular mycorrhiza
2017/4/27
Nearly all organisms live in symbiosis with a vast, diverse array of microbes. Arbuscular mycorrhizal (AM) symbiosis is the interaction between plants and a group of fungi called Glomeromycota. Most l...
Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;101:752–9
Traber plasma deuterium-labeled collard greens
2018/11/13
Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;1...
2017冷泉港亚洲会议：脂质代谢和代谢紊乱（Cold Spring Harbor Asia conference on Lipid Metabolism and Metabolic Disorders）
Lipid Metabolism Metabolic Disorders
2017/1/19
We are pleased to announce the Cold Spring Harbor Asia conference on Lipid Metabolism and Metabolic Disorders which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The ...
Whey protein lowers blood pressure and improves endothelial function and lipid biomarkers in adults with prehypertension and mild hypertension: results from the chronic Whey2Go randomized controlled trial
blood pressure cardiometabolic health milk protein vascular function dairy whey, caseinate angiotensin-converting enzyme inhibition
2018/12/19
Background: Cardiovascular diseases (CVDs) are the greatest cause of death globally, and their reduction is a key public-health target. High blood pressure (BP) affects 1 in 3 people in the United Kin...
Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial
lipid-based nutrient supplements child growth home fortification multiple micronutrients supplementation
2018/12/14
Background: Childhood stunting usually begins in utero and continues after birth; therefore, its reduction must involve actions across different stages of early life.
Choose Your Label wisely:Water-Soluble Fluorophores Often Interact with Lipid Bilayers
Water Proteins Lipid Bilayers Fluorescent Dyes Spectrometry, Fluorescence Protein Binding Solubility
2016/5/25
Water-soluble organic fluorophores are widely used as labels in biological systems. However, in many cases these fluorophores can interact strongly with lipid bilayers, influencing the interaction of ...
Individual Vesicle Fusion Events Mediated by Lipid-anchored DNA
Cholesterol DNA Lipid Bilayers Phosphatidylcholines Phosphatidylethanolamines Membrane Fusion Unilamellar Liposomes
2016/5/25
Membrane fusion consists of a complex rearrangement of lipids and proteins that results in the merger of two lipid bilayers. We have developed a model system that employs synthetic DNA-lipid conjugate...
Formation and Analysis of Topographical Domains Between Lipid Membranes Tethered by DNA Hybrids of Different Lengths
Cell Membrane DNA Membrane Lipids Lipid Bilayers 1,2-Dipalmitoylphosphatidylcholine Microscopy, Fluorescence Base Sequence Molecular Sequence Data Models,Chemical Unilamellar Liposomes
2016/5/25
We recently described a strategy to prepare DNA-tethered lipid membranes either to fixed DNA on a surface or to DNA displayed on a supported bilayer [Boxer et al., J. Struct. Biol., 2009, 168, 190; Bo...
Vesicle Fusion Observed by Content Transfer Across a Tethered Lipid Bilayer
Endoplasmic reticulum-associated degradation (ERAD) ubiquitin-proteasome system (UPS) gp78/RNF45 Epidermal growth factor receptor (EGFR) Exosome Duffy antigen receptor for chemokine (DARC)
2016/5/25
Synaptic transmission is achieved by exocytosis of small, synaptic vesicles containing neurotransmitters across the plasma membrane. Here, we use a DNA-tethered freestanding bilayer as a target archit...
Stability of DNA-Tethered Lipid Membranes with Mobile Tethers
Metallic glasses Rapid-solidification Microstructure Mechanical properties
2016/5/25
We recently introduced two approaches for tethering planar lipid bilayers as membrane patches to either a supported lipid bilayer or DNA-functionalized surface using DNA hybridization (Chung, M.; Lowe...
Covalent Attachment of Lipid Vesicles to a Fluid-Supported Bilayer Allows Observation of DNA-Mediated Vesicle Interactions
Caspian and Black Sea waters reverse-osmotic desalination Na-zeolite softening of the permeate
2016/5/25
Specific membrane interactions such as lipid vesicle docking and fusion can be mediated by synthetic DNA-lipid conjugates as a model for the protein-driven processes that are ubiquitous in biological ...
Effects of Linker Sequences on Vesicle Fusion Mediated by Lipid-Anchored DNA Oligonucleotides
DNA machine synthetic biology
2016/5/25
Synthetic lipid-oligonucleotide conjugates inserted into lipid vesicles mediate fusion when one population of vesicles displays the 5'-coupled conjugate and the other the 3'-coupled conjugate, so that...
Lipid-anchored DNA Mediates Vesicle Fusion as Observed by Lipid and Content Mixing
DNA Vesicles Lipids Fuses
2016/5/25
A general method for synthesizing 5(')- and 3(')-coupled DNA-lipid conjugates has been developed and employed in DNA-mediated vesicle fusion. Vesicles presenting complementary DNA fuse, resulting in b...