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Development of Mass Spectrometry-Based Methods for Quantitation and Characterization of Protein Drugs: Transferrin as a Model Drug Delivery Vehicle
Mass Spectrometry O18 labeling Protein quantitation Transferrin
2014/11/20
In the last two decades, protein drugs have enjoyed a rapid growth and achieved a tremendous success in treating human diseases. However, the presence of physiological barriers greatly impedes the eff...
Electro-oxidation of some non-steroidal anti-inflammatory drugs on an alumina nanoparticle-modified glassy carbon electrode
Modified electrode alumina nanoparticle electrocatalysis
2010/10/14
The electro-oxidation of mefenamic acid, diclofenac, and indomethacin on glassy carbon and alumina nanoparticle-modified glassy carbon electrodes in a phosphate buffer solution at physiological pH was...
Analyses of Non-steroidal Anti-inflammatory Drugs in Environmental Water Samples with Microemulsion Electrokinetic Chromatography
Non-steroidal Anti-inflammatory Drugs Environmental Water Samples Microemulsion Electrokinetic Chromatography
2010/9/13
In this study, a microemulsion electrokinetic chromatography (MEEKC) was used to analyze ten non-steroidal anti-inflammatory drugs (NSAIDs) in water samples. The type and ratio of organic modifiers we...
Development of Signaling Echo Method for Cell-based Quantitative Efficacy Evaluation of Anti-cancer Drugs in Apoptosis without Drug Presence Using High-precision Surface Plasmon Resonance Sensing
Signaling Echo Method Cell-based Quantitative Efficacy Evaluation Anti-cancer Drugs
2010/9/20
We propose a rapid and label-free quantitative evaluation of anti-cancer drug efficacy in apoptosis using live cancer cells cultured on a sensor chip. The resultant custom-made, high-precision surface...
Preparation and Potentiometric Study of Promethazine Hydrochloride Selective Electrodes and Their Use in Determining Some Drugs
Promathazine-HCl selective electrodes phosphotungstic acid promethazine determination
2010/4/16
Promethazine hydrochloride selective electrodes were constructed based on promethazine-phosphotun- gstic acid ion pair in PVC matrix membrane. The plasticizers used were di-butyl phosphate (DBP), tri-...
Determination of Drugs in Blood Samples by High Performance Liquid Chromatography Using On-Line Sample Pretreatment Technique
high performance liquid chromatography on-line column switching
2007/12/13
Determination of Drugs in Blood Samples by High Performance Liquid Chromatography Using On-Line Sample Pretreatment Technique。
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) as Donor Ligands in Organotin(IV) Derivatives: Synthesis, Spectroscopic Characterization and Biological Applications
Derivatives Synthesis Spectroscopic Characterization Biological Applications
2010/4/20
Some new di- and tri-organotin(IV) derivatives of 4 different non-steroidal anti-inflammatory drugs (NSAIDs) with the general formulae R2SnL2 and R3SnL (where R = n-C8H17 and C6H5CH2) and L = 2-[(2,3-...
Preparation, Spectroscopic Studies and Biological Activity of Mono-organotin(IV) Derivatives of Non-Steroidal Anti-inflammatory Drugs
Mono-organotin(IV) derivatives non-steroidal anti-inflammatory drugs biological activity
2010/4/20
A set of 14 mono-organotin(IV) derivatives of general formulae n-BuSnClL2 and n-BuSnL3, where `L' are various non-steroidal anti-inflammatory drugs (NSAIDs), were synthesized and structurally characte...