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A typical bacterial genome contains more than 4,000 genes, which encode all of the proteins that the cells need to survive. How do cells know just how much of each protein they need for their everyday...
Semisynthetic green fluorescent proteins (GFPs) can be prepared by producing truncated GFPs recombinantly and assembling them with synthetic beta-strands of GFP. The yield from expressing the truncate...
The role of N -linked glycans in protein quality control in the early secretory pathway
ER quality protein abnormal protein protein degradation the cavity cytosol proteasome chitosan tyrosine
2014/12/11
The ER quality control machinery maintains the fidelity of the protein maturation process by sorting aberrant proteins for ER-associated protein degradation (ERAD), a process requiring retranslocation...
The role of the ER glucosyltransferase in the quality control of glycoprotein maturation
Pure sciences Biological sciences Endoplasmic reticulum Glycoprotein Glycoprotein glucosyltransferase 1 Protein folding Protein maturation Glucosyltransferase
2014/12/11
N-linked glycans serve as quality control tags in the eukaryotic secretory pathway. The endoplasmic reticulum (ER) protein UDP-glucose: glycoprotein glucosyltransferase 1 (GT1) is the main enzyme that...
The Role Of Edem1 In The Quality Control And Degradation Of Misfolded Glycoproteins
Biological sciences Degradation Glycoproteins Misfolded Protein misfolding
2014/12/10
Immature or incompletely assembled proteins that do not fold correctly are retained in the endoplasmic reticulum (ER) by quality control factors. Terminally misfolded glycoproteins are eventually sort...
期刊信息
篇名
Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis
语种
英文
撰写或编译
撰写
作者
Zhang Z(通讯作者),Xu Y...