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Selenoprotein Biosynthesis and Selenium-Specific Enzymes
selenocysteine selenoprotein selenocysteine lyase
2009/3/23
Selenocysteine lyase (SCL) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that specifically acts on L-selenocysteine to yield L-alanine and selenium. The enzyme does not act on L-cysteine at all. ...
Characterization of Human Selenocysteine Synthase Involved in Selenoprotein Biosynthesis
selenoprotein selenocysteine synthase selenium human
2009/3/16
Bacterial selenocysteine synthase is a pyridoxal 5'-phosphate-dependent enzyme that catalyzes the conversion of seryl-tRNASec to selenocysteyl-tRNASec for selenoprotein biosynthesis. Human selenocyste...
Thioredoxin Reductase 1 Is Important for Selenoprotein Biosynthesis in HeLa Cells
thioredoxin reductase selenoprotein RNAi selenium HeLa cell
2009/3/16
Selenium, an essential trace element, is co-translationally incorporated into selenoproteins as the 21st amino acid selenocysteine. Selenite serves as an inorganic selenium source for selenoprotein bi...