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Multimodality Imaging Methods for Assessing Retinoblastoma Orthotopic Xenograft Growth and Development
Retinal cell tumor Growth and Development
2014/11/25
Genomic studies of the pediatric ocular tumor retinoblastoma are paving the way for development of targeted therapies. Robust model systems such as orthotopic xenografts are necessary for testing such...
The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties
Murine Retinoblastoma Cel mmunohistochemical Features
2014/11/25
HumanretinoblastomaarisesfromanundefineddevelopingretinalcellafterinactivationofRB1.ThisisemulatedinamurineretinoblastomamodelbyinactivationofpRBbyretinal-specificexpressionofsimianvirus40largeT-antig...