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From Evidence to Action: Advocating for comprehensive sexuality education
Young people and adolescents comprehensive sexuality education
2014/3/28
A resource to help service providers, programme planners, policy makers and young people look critically at the sexuality education programmes and curricula in their country.
Evidence for age-dependent changes in Sertoli cell androgen receptor concentration
age-dependent changes Sertoli cell receptor concentration
2009/2/23
Cytosol and nuclear receptor concentrations in Sertoli cells isolated from the testes of 15-, 25-, and 35-day-old rats were measured using hydroxylapatite separation procedures. In these cells the m...
Evidence for a role of cyclooxygenase（prostaglandin synthetase）and prostaglandins in the sperm acrosome reaction and fertilization
spermatozoa fertilization acrosome reaction cyclooxygenase prostaglandin inhibitor
2009/2/23
Three cyclooxygenase (prostaglandin synthetase) inhibitors, indomethacin, phenylbutazone, and oxyphenbutazone, decreased fertilization in vitro when mixed with capacitated mouse spermatozoa before a...
The heterogeneity of rat androgen binding protein（rABP）in the vascular compartment differs from that in the testicular tubular lumen. Further evidence for bidirectional secretion of rABP
rat ABP ABP heterogeneity
2009/2/23
Fractionation of testicular extracts and serum on a Concanavalin A-Sepharose column resolved two peaks of immunoreactive rat androgen binding protein. The rat androgen binding protein in the first pea...
Evidence that estrogen regulation of testosterone secretion in adult rams is mediated by both indirect（gonadotropin dependent）and direct（gonadotropin independent）means
estrogen regulation testosterone secretion adult rams
2009/2/23
Involvement of endogenous estrogen in the regulation of gonadotropin and testosterone secretion was investigated in adult rams. Groups of four rams were either passively immunized against estradio...
Evidence for the presence of androgen receptors in purified rat Leydig cells
androgen receptors purified rat Leydig cells
2009/2/19
Leydig cells, purified on two sequential Percoll gradients to purities of 89 +/- 1%, were used to study the binding of 17-beta-hydroxy-17 alpha-methyl-estra-4,9,11-triene-3-one(3H-R1881). The accumu...
Evidence for Maturational Changes During Epididymal Transit
sperm epididymis egg binding rat
2009/2/19
A study in vitro of interactions between uncapacitated rat spermatozoa and freshly ovulated rat oocytes showed that testicular spermatozoa were unable to adhere to the zona pellucida. On the other h...
Evidence for a Role of Post-Ovulatory Cumulus Components in Supporting Fertilizing Ability of Hamster Spermatozoa
fertilization in vitro capacitation acrosome reaction egg-cumulus complex golden hamster
2009/2/19
A completely chemically defined culture medium was used to investigate the role of egg-cumulus complex (ECC) components in supporting sperm fertilizing ability. Defined sperm motility-stimulating ...
Evidence for Direct Transfer of 1,2-3H Testosterone From Testicular Veins to the Rete Testis in Rats
spermatic vein rete testis fluid
2009/2/19
To investigate the origin and route of entry of testosterone into the rat rete testis, samples were drawn from the rete, deep testicular veins, testicular lymph and systemic arteries during testic...
Evidence that in a physiological setting Sertoli cell number is the major determinant of circulating concentrations of inhibin B in the adult male rhesus monkey（Macaca mulatta）
Sertoli cell number circulating concentrations inhibin B adult male rhesus monkey
2009/2/18
The relationship between changes in Sertoli cell number and function and changes in circulating inhibin B concentrations was investigated following unilateral orchidectomy (UO) in the adult rhesus...
Evidence for catecholaminergic, neuronlike cells in the adult human testis：changes associated with testicular pathologies
catecholaminergic neuronlike cells adult human testis
2009/2/18
Neuronlike, catecholaminergic cells expressing tyrosine-hydroxylase (TH) have recently been found in the testis of a nonhuman primate species, the rhesus monkey. We examined whether neuronlike cel...
Evidence for the role of heterotrimeric guanine nucleotide-binding regulatory proteins in the regulation of the mouse sperm adenylyl cyclase by the egg's zona pellucida
Pertussis toxin acrosome reaction mastoparan cyclic
2009/2/18
Sperm acrosomal exocytosis is the result of a complex set of signal transduction pathways activated physiologically by the egg's extracellular matrix, the zona pellucida. In the mouse, the zona pe...
Evidence for the regulation of prostatic oxytocin by gonadal steroids in the rat
Testosterone dihydrotestosterone 5a-reductase finasteride
2009/2/18
Oxytocin and its receptor are present in the mammalian prostate, and the peptide has been shown to increase prostatic growth, 5alpha-reductase activity, and contractility. This study was performed...
Evidence for cross-talk between Sertoli and germ cells using selected cathepsins as markers
cross-talk Sertoli germ cells
2009/2/18
To examine whether proteases are possibly involved in cellular migration and/or spermiation when developing germ cells translocate across the seminiferous epithelium during spermatogenesis, in sit...
Evidence for nitric oxide regulation of hamster sperm hyperactivation
Sperm motility nitric oxide synthase sodium nitroprusside
2009/2/17
Involvement of reactive oxygen species has been implicated in the process of hyperactivation and capacitation of sperm. Nitric oxide has recently been found to function both as an intracellular a...