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Novel microwave-induced photodynamic therapy could target deeply situated tumors
Novel microwave-induced photodynamic therapy deeply situated tumors
2016/11/4
Physicists at The University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within s...
Novel therapeutics and preclinical imaging for pancreatic cancer – view from the lab
Pancreatic cancer damaging disease tumor microenvironment fibrosis and cancer cells
2017/2/22
Pancreatic cancer is a devastating disease with a five-year survival rate of 6%. A key driver of disease progression is the tumour microenvironment, which is characterised by fibrosis. A dynamic inter...
IDENTIFICATION OF NOVEL SMALL MOLECULE INHIBITORS OF PROTEINS REQUIRED FOR GENOMIC MAINTENANCE AND STABILITY
RPA cancer DNA repair
2015/5/25
Targeting uncontrolled cell proliferation and resistance to DNA damaging chemotherapeutics using small molecule inhibitors of proteins involved in these pathways has significant potential in cancer tr...
Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy
Cancer Chemotherapy Base Excision Repair DNA Repair
2015/5/25
The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of the damaged base by a DNA glycosylase creates an apurini...
Tumour cells secrete small membrane vesicles (30-100nm) termed exosomes, that are derived from late endosomal compartments of cells. Exosomes are increasingly being recognised for their role in interc...
Novel radiation techniques – a personalised approach for patients with rectal cancer
patients rectal cancer
2015/4/7
Surgery remains the standard of care for most rectal cancer as it offers the best chance of cure. However, for patients with early stage low rectal cancers there are several treatment options availabl...
TOWARDS DISCOVERY OF NOVEL TUMOUR MARKERS FOR HEAD AND NECK CANCERS
NECK CANCERS NOVEL TUMOUR MARKERS
2015/3/20
Recent advances in genomic technology, in particular gene expression profiling, may elucidate novel tumour markers
or signatures that will predict how various tumours will behave and respond to vario...
Vertebroplasty in oncology: a novel approach to pain relief in the cancer patient
Vertebroplasty in oncology pain relief cancer patient
2015/3/18
The mechanism by which vertebroplasty is effective in providing pain relief is unclear, but may involve destruction of nerve endings consequent upon the injection of bone cement into the vertebral bod...
Argonne scientists discover novel materials approach to fighting cancer
Argonne scientists novel materials cancer
2010/2/24
Scientists from the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago Medical Center are shaking up the world of materials science and cancer research on the cover ...
Taking aim at aggressive cancer cells--Researchers use novel stem-cell method to discover chemical with potency against breast tumors in mice
cancer cells stem-cell method breast tumors mice
2009/8/18
A team of researchers led by the Whitehead and Broad Institutes has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed n...
NOVEL APPROACH TO IMMUNOTHERAPY FOR EPITHELIAL CANCERS,BONE AND SOFT-TISSUE SARCOMAS
Apoptosis proteins caspase clinical trials cytotoxic T-lymphocytes epithelial cancers gastric cancer antigen osteosarcoma antigen
2009/7/15
The identification of tumor antigens recognized by cytotoxic T-lymphocytes and subsequent clinical trials using peptide immunization have shown tumor regression in advanced malignant melanoma patients...
A Novel Method of Reporting c-erbB-2 Overexpression;Correlation With Grade but not With Other Prognostic Parameters in Breast Cancer
c-erbB-2 HER-2/neu breast cancer grade
2009/6/24
Overexpression of erbB-2 protein is a marker of clinically aggressive behavior in breast cancer patients. In general erbB-2 status is reported on a scale from negative to 3+, depending on staining int...
Measurement of total antioxidant response in colorectal cancer using a novel automated method
Oxidative stress Colorectal neoplasm Total antioxidant capacity
2010/1/12
Aim: The aim of this study was to compare the antioxidative status in patients with colorectal cancer and healthy controls, based on measurements made using a novel method. Materials and Methods: The ...
期刊信息
篇名
Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects.
语种
英文
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撰写
作者
Tong YG.,Zhang XW.,Tian F.,Yi YH.,Xu QZ.,Li L.,Tong LJ.,Lin LP.,Ding J...
期刊信息
篇名
Conformation and antitumor activity of novel metal complexes of piperazinedithioformates
语种
英文
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撰写
作者
He,Fei; Huang,Hui; Yin,Fu-ling; Li,Run-tao; Lei,Xiao-ping; Zeng,Hui-hui
第一作者单位
Peking...