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De novo phasing resolves haplotype sequences in complex plant genomes
de novo phasing haplotype-resolved assembly autopolyploid chromosomal rearrangement
2023/11/28
Genome phasing is a recently developed assembly method that separates heterozygous eukaryotic genomic regions and builds haplotype-resolved assemblies. Because differences between haplotypes are ignor...
SCR-22 of pollen-dominant S haplotype class is recessive to SCR-44 of pollen-recessive S haplotype class in Brassica rapa
SCR-22 pollen-dominant S haplotype SCR-44 Brassica rapa
2023/8/9
SCR/SP11 encodes the male determinant of recognition specificity of self-incompatibility (SI) in Brassica species and is sporophytically expressed in the anther tapetum. Based on dominance relationshi...
Linkage Disequilibrium and Haplotype Block Structure in Portuguese Holstein Cattle
single nucleotide polymorphism GWAS dairy cattle
2018/3/5
The objectives of this study were to estimate linkage disequilibrium (LD), describe and scan a haplotype block for
the presence of genes that may affect milk production traits in Portuguese Holstein ...
The Association between Human Leukocyte Antigen Class II DR3–DQ2 Haplotype and Type 1 Diabetes in Children of the East Azerbaijan State of Iran
Haplotype Genotype HLA-DRB1 HLA-DQB1
2015/11/9
Background: Type 1 diabetes mellitus (T1D) is an autoimmune disease. Several associations between human leukocyte antigen (HLA) complex and T1D were found in various populations. Associations with var...
Strategies for haplotype-based association mapping in a complex pedigreed population
complex pedigree false positives
2015/6/23
In association mapping, haplotype-based methods are generally regarded to provide higher
power and increased precision than methods based on single markers. For haplotype-based association
mapping...
The dopamine transporter haplotype and reward-related striatal responses in adult ADHD
ADHD Striatum DAT1 gene Genetic imaging Reward Dopamine
2015/4/24
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable disorder and several genes increasing disease risk have been identified. The dopamine transporter gene, SLC6A3/DAT1, has been stud...
Haplotype inference and haplotype-based transmission disequilibrium test (Hap-TDT)
Haplotype inference Transmission Disequilibrium Test Haplotype-based TDT
2016/12/20
Haplotype inference and haplotype-based transmission disequilibrium test (Hap-TDT) .
Characterization of S haplotype in a new self-compatible Brassica rapa cultivar Dahuangyoucai
Brassica rapa L. gene expression M-locus protein kinase (MLPK) S-locus genes self-incompatibility
2014/2/24
The most important Brassica species, B. rapa, is naturally self-incompatible. Self-compatible mutants would be useful for dissecting the molecular mechanism of self-incompatibility (SI), a process tha...
An Efficient Algorithm for Haplotype Inference on Pedigrees with a Small Number of Recombinants
computational biology, haplotype inference, pedigree, recombinare combination,algorithm, probabilistic model.
2012/12/3
Combinatorial (or rule-based) methods for inferring haplotypes from genotypes on a pedigree have been studied extensively in the recent literature. These methods generally try to reconstruct the haplo...
Haplotype based association study between t-PA gene and essential hypertension
Haplotype based association study t-PA gene essential hypertension
2009/4/20
Several previous studies have shown that essential hypertension (EH) is associated with fibrinolysis. Tissue plasminogen activator (t-PA) plays a key role in fibrinolysis. Thus, it is possible that ...
Association between Interleukin-10 Gene Promoter Haplotype and Schizophrenia in a Han-Chinese Study
schizophrenia IL-10 promoter region haplotypic analysis community
2009/4/14
Schizophrenia is a multi-factorial genetic disease, and it is caused by a combination of different gene polymorphisms and not individual ones, however, its pathogenesis is still unclear. The purpose o...
EST-SNPs in bread wheat: discovery, validation, genotyping and haplotype structure
contigs DNA polymorphism DNA sequencing homoeologue sequence variants (HSVs) Triticum aestivum L.
2014/3/11
The present study involves discovery, validation and use of single-nucleotide polymorphisms (SNPs) in bread wheat utilizing 48 EST-contigs (individual contigs having 20-89 ESTs, derived from 2 to 11 d...
The nonprogressive motility of sperm populations from mice with a tw32 haplotype
nonprogressive motility sperm populations mice tw32 haplotype
2009/2/19
We have previously reported that epididymal spermatozoa from mice carrying a tw32 haplotype have a lower net velocity than do spermatozoa from congenic +/+ males. Using a test for nonprogressive mot...
Follicle-Stimulating Hormone Receptor Gene Haplotype Distribution in Normozoospermic and Azoospermic Men
Male infertility polymorphism SNP testis azoospermia
2008/12/23
The human follicle-stimulating hormone (FSH) receptor (FSHR) gene possesses single nucleotide polymorphisms (SNP) in exon 10, which influence serum FSH levels in women, but not in men. In the presen...
摘要
3.84, P3.84, P<0.05）, and they were strong linkage disequilibria. The polymorphisms and haplotypes distributions of MICA and MICB microsatellite locus in Guangzhou Han population have their own g...